Animal Studies Using CBD for Pets In investigating CBD’s potential for human use, many researchers are using animals for their investigations. While these results are meant to be extrapolated to humans, they show promising results for animals.
Animal Studies Using CBD for Pets
In investigating CBD’s potential for human use, many researchers are using animals for their investigations. While these results are meant to be extrapolated to humans, they show promising results for animals.
Studies show that animal models demonstrate the anti-epileptic potential of cannabis and suggest that CBD may enhance the efficacy in preclinical models of epilepsy.
Another indicates that CBD restores liver function, normalizes 5-HT levels and improves brain pathology in accordance with normalization of brain function, in dealing with hepatic encephalopathy, a syndrome observed in patients with end-stage liver disease.
Yet another shows that the anti-emetic effect of cannabinoids has been shown across a wide variety of animals that are capable of vomiting in response to a toxic challenge.
These are just a small sampling of the studies investigating animals and their responses to CBD.
There are even clinical trials in place to specifically investigate the use of CBD for pets and their unique issues. Researcher Dr. Stephanie McGrath is assessing the efficacy of CBD in treating canine epilepsy.
“The CBD product is very low in the psychoactive component of cannabis, THC, making it safe for use in dogs. Each dog will be randomly assigned to receive either CBD or a placebo for 12 weeks and then switch to the opposite medication for an additional 12 weeks.”
McGrath is also undertaking a study to assess the efficacy of CBD in treating canine osteoarthritis. Here, each dog will receive a placebo or CBD oil for 6 weeks.
Then they will receive the opposite for the subsequent 6 weeks. According to the Cannabist, the stakes are high for the epilepsy study, particularly as about 30 percent of dogs on conventional anti-seizure therapies continue to have uncontrolled seizures.
“It’s imperative, really, that we find a drug or drugs that are able to control seizures in dogs — and humans, for that matter,” McGrath told the Cannabist.
Why CBD May Work For Pets
It all comes down to the endocannabinoid system, which is present in humans and many other animals.
We have cannabinoid receptors in our brain and body, which make up the endocannabinoid system. They respond to endogenous, or internally created cannabinoids, and exogenous, or introduced cannabinoids.
Natural endocannabinoid substances are synthesized by our bodies, but can lag behind what we actually need. CBD, unlike THC, does not bind to cannabinoid receptors. Instead, it increases the amount of endocannabinoids in the body’s system.
Because this system exists in both humans and our pets, we see similar effects in all parties. While animals metabolize CBD and other cannabinoids differently than humans, studies into pets and CBD are helping people to understand the exact process for the most advantageous treatment.
Case Studies Using CBD for Pets
There are many case studies and anecdotal evidence suggesting CBD can be not just okay to give to pets, but good for them.
An Australian holistic veterinarian, Dr. Edward Bassingthwaighte, shares a few cases. A dog with a fast-growing tumor in her mammary gland, treated with CBD oil, had her tumor shrink over three months with no recurrence three months later; a Jack Russel with a heart murmur and painful arthritis received CBD and became much more active and happy after a month of treatment.
David Bourgoin’s 11-year-old dog sustained a shoulder injury, which then developed a cyst.
“Knowing what I know about CBD, I decided this is what I needed to do for him,” said Bourgoin in an NBC 7 interview. “I have to give him the best shot I can.”
According to Bourgoin, after CBD treatment his dog became more active and can spend more time playing like a puppy.
Kiki Kane wrote an article about her elderly cat Zaphod, who she said “lost his purr, his eyesight, and his ability to comfortably jump, pounce, play, and recently, even cuddle.”
She described the cat as being angry and lethargic, sleeping during the day, and walking in circles at night while “occasionally meowing existentially into the darkness.”
Kane started dosing Zaphod with CBD oil, noting:
“I tried half a dose twice a day, which seemed to be just enough to relax his facial expression and let him feel comfortable being picked up, held, or petted. The CBD oil doesn’t stop his night restlessness but it does relax him enough that I can carry him to bed with me and he’ll settle on my chest. I know we’ll be saying goodbye very soon, and no miracle drug will change that, but I’m so happy that I can offer a little more comfort as the light continues to fade.”
Will My Pet Get High?
Some pet owners may be nervous to use hemp products for their pets because of fears that their pet will experience psychoactive effects.
On PetMd, Dr. Gary Richter, owner and medical director of Montclair Veterinary Hospital in Oakland, California, says that CBD oil has no psychoactive effect on dogs when dosed properly.
“Depending on the nature of the product, if it contains little or no THC, then the dog is not going to get high,” he says.
THC toxicity is a concern, but that is only an issue with products containing THC. Because of this, it is important to use high-quality, reputable CBD products for your pets.